Thermo Fisher Applied Biosystems Genetic Analyzers

View CSAF Summary Successful exploitation of this vulnerability could allow an attacker to modify .fsa/.hid output files, tampering with DNA data and resulting in inaccurate test results. The following versions of Thermo Fisher Applied Biosystems Genetic Analyzers are affected: Applied Biosystems 3500/3500xL Series Data Collection Software <=4.0.2 Applied Biosystems 3730/3730xL Series Data Collection Software <=5.0.2 Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software <=1.2.5 Applied Biosystems SeqStudio Flex Series Instrument Software <=1.2.0 Applied Biosystems GeneMapper ID-X Software <=v1.7.3 Applied Biosystems 3130 Series Data Collection Software <=4.1 ABI PRISM 3100/3100-Avant Data Collection Software <=2.0 ABI PRISM 310 Data Collection Software <=3.1 CVSS Vendor Equipment Vulnerabilities v3 8.4 Thermo Fisher Thermo Fisher Applied Biosystems Genetic Analyzers Missing Support for Integrity Check Background Critical Infrastructure Sectors: Healthcare and Public Health Countries/Areas Deployed: Worldwide Company Headquarters Location: United States Vulnerabilities Expand All + CVE-2026-17583 The affected product is vulnerable because its .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes. View CVE Details Affected Products Thermo Fisher Applied Biosystems Genetic Analyzers Vendor: Thermo Fisher Product Version: Thermo Fisher Applied Biosystems 3500/3500xL Series Data Collection Software: <=4.0.2, Thermo Fisher Applied Biosystems 3730/3730xL Series Data Collection Software: <=5.0.2, Thermo Fisher Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software: <=1.2.5, Thermo Fisher Applied Biosystems SeqStudio Flex Series Instrument Software: <=1.2.0, Thermo Fisher Applied Biosystems GeneMapper ID-X Software: <=v1.7.3, Thermo Fisher Applied Biosystems 3130 Series Data Collection Software: <=4.1, Thermo Fisher ABI PRISM 3100/3100-Avant Data Collection Software: <=2.0, Thermo Fisher ABI PRISM 310 Data Collection Software: <=3.1 Product Status: known_affected Remediations Mitigation Thermo Fisher has developed security updates to address the vulnerability. The security updates implement the use of digital signatures on the instrument software that adds an extralayer of protection. Moving forward, this will help users verify that data files have not been modified. Vendor fix Applied Biosystems 3500/3500xL Series Data Collection Software: Update to version 4.0.3 https://downloads.thermofisher.com/3500_DCS_v4.0.3_Patch/v4.0.3_Patch_Installer.exe Vendor fix Applied Biosystems 3730/3730xL Series Data Collection Software: Update to version 5.0.3 https://downloads.thermofisher.com/3730xl_UDC_v5.0.3_Patch/3730xl_UDC_v5.0.3_Patch.exe Vendor fix Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software: Update to version 1.2.6 https://downloads.thermofisher.com/SeqStudio/1.2.6/SeqStudio-1.2.6.abpkg Vendor fix Applied Biosystems SeqStudio Flex Series Instrument Software: Update to version 1.2.1 https://downloads.thermofisher.com/SeqStudioFlex/1.2.1/SeqStudioFlex-1.2.1.abpkg Vendor fix Applied Biosystems GeneMapper ID-X Software: Update to version 1.7.4 https://downloads.thermofisher.com/GeneMapperID-Xv1.7.4_Patch/GMIDX_v1.7.4_Patch.exe Vendor fix Applied Biosystems 3130 Series Data Collection Software: Product is End of Life (EoL), no update provided Vendor fix ABI PRISM 3100/3100-Avant Data Collection Software: Product is End of Life (EoL), no update provided Vendor fix ABI PRISM 310 Data Collection Software: Product is End of Life (EoL), no update provided Mitigation For users who are unable to immediately implement all applicable security updates, Thermo Fisher Scientific recommends implementing the following interim mitigation measures until the applicable updates have been installed: -Maintain a secure chain of custody for files generated by the HID instrumentation throughout the analysis workflow. -Sto